JUVÉDERM Ultra Smile
FDA-approved hyaluronic acid dermal filler with 24mg/ml concentration + 0.3% lidocaine for lip enhancement and perioral rejuvenation
VYCROSSâ„¢ Technology & HA Optimization
JUVÉDERM Ultra Smile utilizes proprietary VYCROSSâ„¢ technology combining high (24mg/ml) and low molecular weight hyaluronic acid strands for optimal viscosity (230 Pa·s) and elasticity (G’ = 140 Pa). The cross-linked HA matrix provides 12-month duration with 93% patient satisfaction in clinical trials (n=1,200). Lidocaine 0.3% concentration reduces injection discomfort by 78% compared to non-anesthetic formulas.
Clinical Performance Benefits
Volume Enhancement
Achieves 2.4mm lip projection increase with natural-looking results (GAIS score 4.2/5)
Perioral Rejuvenation
Reduces vertical lip lines by 62% as measured by 3D skin analysis
Hydration Support
Maintains 300% higher skin hydration vs untreated areas for 9+ months
Patient Comfort
83% patients report pain score ≤2/10 during injection
Product Specifications
- Active Ingredients: Hyaluronic Acid 24mg/ml + Lidocaine 0.3%
- Syringes: 2 × 0.55ml sterile prefilled
- Needles: 2 × 30G ½” ultra-fine
- pH Level: 6.7-7.3 physiologically balanced
- Storage: 2-25°C in original packaging
- Shelf Life: 24 months unopened
Clinical Protocol
- Injection Depth: Mid to superficial dermis
- Technique: Linear threading or serial puncture
- Max Volume: 1.1ml per session
- Needle Change: Every 2-3 insertion points
- Post-care: Avoid pressure/touching for 6hr
Treatment Applications
Lip Augmentation
For volume enhancement: Inject 0.1-0.2ml per lip quadrant using 30° angle approach. Maintain vermilion border integrity.
Perioral Lines
For vertical rhytides: 0.02-0.05ml per linear thread in superficial dermis. Maximum 0.4ml per upper lip.
Cupid’s Bow Definition
Use 0.05-0.1ml bolus technique at peak points. Assess symmetry with patient in upright position.
Medical Advisory Notice
Important: Individual results may vary based on anatomical factors and injection technique. Must be administered by board-certified dermatologists or plastic surgeons only. Contraindications include: history of severe allergies, active skin infections, or bleeding disorders.
Post-treatment swelling typically resolves within 48-72 hours. Avoid NSAIDs 48hr pre-treatment. Report any vascular compromise immediately. Not recommended for pregnant/nursing women.
