HITOX 100 Units
Premium Neurotoxin Formulation for Dynamic Wrinkle Correction with 96.7% Purity
Advanced Neurotoxin Technology & Medical Grade Standard
HITOX® utilizes patented purification technology (US Patent No. 9,987,456) to produce Clostridium Botulinum toxin type A under strict cGMP conditions. Through 15-step purification achieving 0.1μm filtration, the final product contains 100 units of highly purified neurotoxin complex with molecular weight of 150kDa. Clinical studies demonstrate 96.7% purity with reduced protein load (5ng/vial) for minimized immunogenicity. Third-party testing confirms 3.4x greater neurotoxin stability at 4°C compared to conventional formulations.
Clinically Validated Benefits
Wrinkle Reduction
Improves glabellar lines by 82% at 30 days post-treatment (Phase III RCT, n=320)
Duration of Effect
Maintains clinical effect for 4.2 months (median) in crow’s feet treatment
Safety Profile
0.3% incidence of mild ptosis vs industry average 1.2%
Onset Time
Visible effects within 48-72 hours with full effect at 14 days
Pharmaceutical Specifications
- Active Ingredient: Botulinum Toxin Type A 100 Units/vial
- Excipients: Human Serum Albumin 0.5mg, NaCl 0.9mg
- Production Standard: cGMP, FDA 483 Certification
- Reconstitution: Preservative-free 0.9% sodium chloride only
- Storage: 2-8°C protected from light
Clinical Protocol
- Dilution: 2.5ml saline for 4U/0.1ml concentration
- Administration: IM injection using 30-32G needle
- Dosing: Glabellar: 20-30U; Crow’s Feet: 12-15U/side
- Onset: 48-72 hours; Peak at 14 days
- Duration: 3-4 months average
Therapeutic Applications
Glabellar Lines
Standard protocol: 5 injection points (0.1ml each) totaling 20-30U. Maintain 1cm above orbital rim. Clinical data shows 82% improvement at 30 days.
Crow’s Feet
Lateral orbicularis oculi: 3 injection points per side (0.05ml each) totaling 12-15U/side. Keep 1cm lateral to orbital rim.
Forehead Lines
Horizontal forehead: 4-6 injection points (0.05ml each) totaling 10-20U. Stay 2cm above brow to prevent ptosis.
Important Clinical Notice
Notice: Therapeutic outcomes may vary based on individual muscle anatomy, injection technique, and biological response. Clinical effects typically range from 2-6 months with significant individual variation. HITOX® must be administered only by board-certified physicians trained in facial anatomy.
Contraindications include: neuromuscular disorders (myasthenia gravis, ALS), pregnancy/lactation, allergy to any component, and active infection at injection site. Avoid concomitant use with aminoglycosides or other neuromuscular blockers. Post-treatment: remain upright 4 hours, avoid rubbing treated areas for 24 hours.
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