Demei Non-Lidocaine
Demei Dermal Fillers, developed by DKBIO Co., Ltd. and EG DONG AN Aesthetic Clinic Network, utilize 20mg/mL high-purity hyaluronic acid and advanced LEDM cross-linking technology. Clinically validated for safety and efficacy, Demei achieves <10ppm heavy metals and minimal BDDE, meeting US FDA and EDQM standards.
Key Advantages of Demei Fillers
- Exceptional Safety: Ultra-low BDDE content and <10ppm heavy metals, with advanced ATER purification for toxin removal.
- Superior Viscoelasticity: Uniform cross-linking delivers a soft, cohesive gel for natural volume and smooth injection.
- Regulatory Approval: Complies with US FDA and EDQM requirements for dermal fillers.
- Long-Lasting Results: Maintains volume and shape for up to 12 months, integrating seamlessly with tissue.
- Patient Comfort: Low extrusion force and smooth texture ensure a comfortable injection experience.
Innovative Manufacturing Technology
LEDM Cross-linking Method
Patented Low-chemical & Enhanced Double Cross-linking (LEDM) ensures a high proportion of fully cross-linked HA, minimizing incomplete bonds for optimal gel stability.
ATER Purification Process
Advanced Technique for Elimination of Residues (ATER) removes residual BDDE and contaminants, ensuring biocompatibility and safety.
Monophasic Gel Structure
Homogeneous HA particle distribution creates a soft, cohesive gel for natural contouring and long-lasting results.
Minimal BDDE Usage
Uses the lowest effective BDDE for cross-linking, with advanced cleaning to ensure residuals are below detection limits.
Demei #1
- Composition: 20mg/mL Hyaluronic Acid
- Gel Type: Moderate viscosity, good elasticity and cohesiveness
- Indications: Superficial and light wrinkle correction
- Applications: Fine facial lines, lips, periocular areas
- Injection Depth: Superficial dermal layer
- Needle Size: 30G x ½” (13mm)
- Duration of Effect: 3 – 6 months
- Packaging: 1 x 1.0 mL pre-filled syringe with 2 sterile needles
- Storage: 1°C to 30°C, avoid sunlight, do not freeze or heat
- Shelf Life: 24 months
Demei #2
- Composition: 20mg/mL Hyaluronic Acid
- Gel Type: Highly viscous, good elasticity and moderate cohesiveness
- Indications: Moderate wrinkle correction, subtle facial contouring
- Applications: Marionette lines, moderate facial wrinkles
- Injection Depth: Superficial dermal layer
- Needle Size: 27G x ½” (13mm)
- Duration of Effect: 10 – 12 months
- Packaging: 1 x 1.0 mL pre-filled syringe with 2 sterile needles
- Storage: 1°C to 30°C, avoid sunlight, do not freeze or heat
- Shelf Life: 24 months
Demei #3
- Composition: 20mg/mL Hyaluronic Acid
- Gel Type: High elasticity and cohesiveness, moderate viscosity
- Indications: Filling deep wrinkles and folds, contouring
- Applications: Forehead, chin, cheek augmentation, nose contouring
- Injection Depth: Deep dermis layer, subcutaneous tissue
- Needle Size: 27G x ½” (13mm)
- Duration of Effect: 10 – 12 months
- Packaging: 1 x 1.0 mL pre-filled syringe with 2 sterile needles
- Storage: 1°C to 30°C, avoid sunlight, do not freeze or heat
- Shelf Life: 24 months
Professional Use & Clinical Indications
Facial Wrinkle Correction
For superficial and moderate wrinkles: Inject Demei #1 or #2 into the superficial dermal layer using 30G or 27G needles. Suitable for fine lines, lips, and marionette lines.
Facial Contouring & Volumizing
For deep folds and volume restoration: Use Demei #3 for forehead, chin, cheek, and nose augmentation. Inject into deep dermis or subcutaneous tissue with 27G needles.
Rejuvenation & V-Line Shaping
Enhance lips, forehead, nose, and chin for a natural V-line. Immediate results with no downtime. Always administered by licensed professionals.
Important Professional Notice
Disclaimer: Clinical outcomes may vary based on individual patient factors. All procedures must be performed by certified medical professionals. Contraindications include hypersensitivity to HA, pregnancy, active infection, and autoimmune disorders.
This product is not intended for self-administration. Demei Fillers are not a substitute for surgical or disease-modifying therapies. Always consult a healthcare provider prior to use.
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