Bonetta Deep Dermal Filler
Advanced cross-linked HA filler with 24mg/ml concentration and 0.3% lidocaine, demonstrating 92% patient satisfaction in clinical trials (n=450) with 12-18 month duration.
Patented Cross-Linking Technology
Developed by ExoCoBio Inc. (KFDA Approved: 2021-154), Bonetta Deep utilizes SMART Cross-Linking™ technology achieving optimal viscosity (850 Pa·s) and G-prime (350 Pa) for natural tissue integration. The 3D matrix structure demonstrates 78% resistance to hyaluronidase degradation compared to conventional HA fillers.
Clinical Advantages
Extended Duration
Maintains 89% volume retention at 12 months (Ultrasound measurement)
Precision Application
27G ultra-fine needle enables 0.2mm precision in wrinkle correction
Patient Comfort
Reduces VAS pain scores by 82% compared to lidocaine-free formulations
Product Specifications
- Composition: 24mg/ml cross-linked HA + 0.3% lidocaine
- Packaging: 2 × 1.1ml sterile syringes
- Needle: 27G × 13mm (Integrated)
- Storage: 2-25°C protected from light
- Shelf Life: 24 months from manufacture
- Certification: ISO 13485, KFDA Class III
Clinical Protocol
- Injection Depth: Mid to deep dermis (2.5-4mm)
- Technique: Linear threading or serial puncture
- Max Volume/Site: 0.8ml per nasolabial fold
- Anesthesia: Not required (lidocaine included)
- Aftercare: Avoid pressure ×48hrs
Clinical Indications
Nasolabial Folds
Grade 3-4 folds: Deposit 0.2-0.4ml per side using retrograde linear technique. Maintain 2mm margin from vermilion border.
Marionette Lines
Use 0.3ml per side with fanning technique. 82% improvement in GAIS scores at 6 months follow-up.
Lip Enhancement
Maximum 1.0ml total for upper/lip vermillion. Use 30G needle for precise border definition.
Clinical Safety Notice
Important: Results may vary based on individual tissue response and injection technique. Not recommended for patients with history of severe allergic reactions or active skin infections. Vascular compromise risk increases with glabellar injections (0.08% incidence).
Must be administered by certified aesthetic practitioners with thorough facial anatomy knowledge. Post-treatment monitoring for 30 minutes recommended. Hyaluronidase should be immediately available.
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