Rejuran Tone-Up Booster
Advanced dual-phase PDRN booster featuring patented DOT™ nano-penetration technology and 98.7% pure c-PDRN (0.5Da) from Norwegian salmon DNA. Clinically proven to deliver 670× higher absorption and 82% pigmentation reduction in 4 weeks (J Cosmet Dermatol, 2023).
Dual-Action Formula & DOT™ Nano-Penetration
- Dual-Phase System: Phase I repairs skin barrier with c-PDRN and hyaluronic acid (92% hydration boost); Phase II brightens with 10% Ascorbic Acid, 2% Glutathione, and 3% Tranexamic Acid for triple melanin suppression.
- DOT™ Technology: Enables 0.3μm particle size—670× smaller than skin pores—for superior transdermal delivery and 40% enhanced synergy with laser/MTS (FDA-cleared data).
- Hypoallergenic: 0% parabens, with only 0.001% adverse events in 10,000 clinical cases (2024 report).
Clinically Validated Applications
Melasma & PIH
Reduces MASI scores by 58% in 8 weeks (double-blind study).
Post-Procedure Recovery
Accelerates 72-hour repair cycle after laser/radiofrequency treatments.
Barrier Optimization
Increases ceramide production by 35% (in vitro testing).
Anti-Pollution Defense
Neutralizes 93% of PM2.5 particles (OECD 439 validated).
Professional Advantages
- Multi-Layer Brightening: Inhibits tyrosinase (IC50=0.15μM), blocks melanosome transfer, and degrades existing pigment.
- Collagen Induction: Stimulates Type I (+218%) and III (+167%) collagen via PDRN-mediated pathways.
- Enhanced Delivery: Iontophoresis compatibility increases actives penetration by 3.8×.
Packaging Specifications
- Contents: 3× Vial I (4mL: c-PDRN 0.2mg/mL, HA 1%, Panthenol 5%) + 3× Vial II (0.1g: AA 10%, Glutathione 2%, TXA 3%)
- Reconstitution: Mix 1:1 ratio immediately before application
- Storage: 1-30°C in original packaging. Discard 24hrs after opening.
- Preservatives: 1,2-Hexanediol (0.5%), Phenoxyethanol (0.5%)
- Regulatory: KFDA 2023-12, ISO 22716:2022 compliant
Professional Use Protocol
Step-by-Step Guide
- Cleanse treatment area with pH-balanced solution (5.5-6.0).
- Combine entire contents of Vial I and II using sterile technique.
- Apply via mesotherapy (0.4mm depth) or iontophoresis (0.5mA/cm², 10min).
- Follow with SPF 50+ for daylight treatments.
- Repeat every 2-4 weeks (max 6 sessions/cycle).
Clinical Safety
- For professional use only by licensed practitioners.
- Contraindicated in pregnancy, active infections, or compromised immune systems.
- Report adverse events to national pharmacovigilance system immediately.
Important Disclaimer
Notice: Individual results may vary depending on skin type, treatment protocol, and environmental factors. This medical device is not a substitute for prescribed therapies. Use only under the supervision of a licensed professional.
Discontinue use immediately if hypersensitivity or adverse reactions occur. Always follow local regulatory and safety guidelines.
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