Muchcaine Plus 5% Prilocaine
Muchcaine PRO is a professional-grade topical anesthetic cream featuring a 2.5% Lidocaine HCl and 2.5% Prilocaine dual-action formula (EMLA-equivalent). Clinically validated to deliver rapid-onset dermal anesthesia within 25–35 minutes, it provides up to 120 minutes of effective pain control for cosmetic and dermatological procedures[1,2].
Key Advantages
- Dual-Action Efficacy: 2.5% Lidocaine + 2.5% Prilocaine for synergistic, broad-spectrum anesthesia
- Rapid Onset: Achieves effective numbness in 25–35 minutes (mean onset: 28.7 min[1])
- Extended Duration: Maintains anesthesia for 60–120 minutes, supporting longer procedures
- pH-Balanced Formula: pH 7–8 minimizes skin irritation and supports barrier function
- Occlusion-Enhanced Absorption: Plastic wrap method increases dermal penetration by up to 2.4×[2]
- Medical-Grade Quality: Meets EMLA formulation standards; suitable for microneedling, laser, and tattoo procedures
Anesthetic Technology & Mechanism
Amide-Type Local Anesthetics
Lidocaine and Prilocaine reversibly block voltage-gated sodium channels in neuronal membranes, inhibiting depolarization and impulse conduction for effective sensory blockade.
Optimized Emulsion Base
The oil-in-water emulsion ensures homogeneous API distribution and enhances stratum corneum penetration, maximizing anesthetic efficacy and patient comfort.
Occlusion-Enhanced Delivery
Occlusive dressing (plastic wrap) increases percutaneous absorption, accelerating onset and deepening anesthesia for high-demand clinical settings.
Product Specifications
- Active Ingredients: Lidocaine HCl 2.5%, Prilocaine 2.5%
- Net Weight: 500g/tub
- Appearance: White to yellowish oil-in-water emulsion
- Preservatives: Methylparaben (1.5mg/g), Propylparaben (0.4mg/g)
- Vehicle: Liquid paraffin, glycerin monostearate, carbomer 940
- Packaging: HDPE container with tamper-evident seal
Professional Use Protocol
- Preparation: Clean area with pH-neutral, alcohol-free cleanser
- Application: Apply 2–3mm thick layer (≈2g/10cm²)
- Occlusion: Cover with plastic wrap (not for mucous membranes)
- Onset Time: 25–35 minutes
- Duration: Up to 120 minutes
- Removal: Remove cream completely before procedure
- Patch Test: Conduct 24h prior to full application
Clinical Applications
Microneedling & Laser
Apply 2g/10cm², occlude for 30 minutes. Provides consistent anesthesia for fractional laser, RF microneedling, and IPL treatments.
Tattoo & PMU
For tattooing or permanent makeup, apply a thick layer and occlude for 35 minutes. Reduces pain and movement, improving procedural accuracy.
Dermatological Procedures
Suitable for superficial dermatological interventions (e.g., curettage, superficial excisions). Not for ophthalmic or mucosal use.
Important Safety Notice
Notice: Individual anesthetic response may vary due to skin thickness, vascularization, and metabolic factors. For external use only. Not for ophthalmic or mucosal application. Discontinue use if hypersensitivity occurs. Keep out of reach of children.
Effectiveness may differ between individuals. All procedures should be performed by licensed professionals. Always conduct a patch test prior to full application.
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