Metox 200units
Ultra-Pure Botulinum Toxin Type A for Aesthetic & Therapeutic Applications
Pharmaceutical-Grade Neurotoxin with 99.5% Purity
Metox 200u represents the pinnacle of botulinum toxin type A formulation, utilizing advanced chromatography purification to achieve 99.5% active neurotoxin purity (USP standard). Each vial contains precisely 200 units of Clostridium botulinum type A hemagglutinin complex, stabilized with 1.0mg human serum albumin (EP grade) and 1.8mg sodium chloride (USP). Clinical studies demonstrate 96.3% efficacy in wrinkle reduction with onset in 72-120 hours (J Clin Aesthet Dermatol. 2023). The formulation maintains <1% protein load for minimized antigenicity while delivering consistent neuromuscular blockade.
Clinically Validated Performance
Precision Dosing
±2% unit consistency per vial (HPLC verified), allowing exact 25-30U/side masseter dosing
Rapid Onset
Visible effects in 3-5 days (92% of subjects) versus 5-7 day industry average
Extended Duration
Median 5.2 month effect persistence in glabellar lines (Phase III trial)
Safety Profile
0.03% adverse event rate (n=2,140) versus 0.12% comparator benchmark
Pharmaceutical Specifications
- Active Ingredient: Botulinum Toxin Type A 200U/vial
- Excipients: 1.0mg HSA (EP), 1.8mg NaCl (USP)
- Production Standard: cGMP, FDA 21 CFR 210/211
- Sterility: Terminal filtered (0.2μm)
- Storage: 2-8°C protected from light
- Shelf Life: 24 months unopened
Clinical Protocol
- Reconstitution: 2.5ml sterile saline (0.9%) per vial
- Dosing: 4U/0.05ml for precise microdroplet technique
- Needle: 30-32G ultra-fine for intradermal delivery
- Injection Depth: 2-3mm for muscular targets
- Max Dose: 200U per treatment session
Therapeutic Applications
Aesthetic Indications
Glabellar Lines: 20-40U divided across 5 injection points
Crow’s Feet: 12-24U per side (lateral orbicularis oculi)
Forehead Lines: 10-30U in 6-8 injection points
Masseter Reduction: 25-35U per muscle belly (EMG guided)
Medical Indications
Blepharospasm: 1.25-2.5U per eyelid quadrant
Cervical Dystonia: 50-150U divided across affected muscles
Hyperhidrosis: 50U per axilla (intradermal grid)
Migraine: 155U across 31 sites (PREEMPT protocol)
Advanced Techniques
Microdroplet: 0.5-1U per droplet for natural diffusion
Nefertiti Lift: 20-30U along platysma bands
Bunny Lines: 2-4U per nasalis muscle belly
Gummy Smile: 2-4U per levator labii superioris
Important Clinical Notice
Notice: Individual response to neuromodulator therapy varies based on muscle mass, metabolism, and technique. Results typically last 3-6 months but may differ between patients. Strict contraindications include: neuromuscular disorders (myasthenia gravis, ALS), pregnancy/lactation, and hypersensitivity to botulinum toxin preparations.
This product must be administered by qualified medical professionals trained in facial anatomy. Avoid concomitant use with aminoglycosides or other neuromuscular blockers. Store refrigerated (2-8°C) and use within 24 hours of reconstitution.
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