Is Innotox stronger than Botox

Innotox and Botox each have their advantages. Innotox works faster, precisely targeting within 2 hours and lasting 6 – 8 months. Botox is classic and stable. In terms of muscle paralysis accuracy, Innotox reaches 97.3%, slightly higher than Botox’s 82.6%.

Korean “Toxin King” Arrives

Last month, the alarm at a medical beauty clinic in Hangzhou suddenly went off—A 25-year-old customer’s face swelled up like a bun after getting an injection of a certain imported botulinum toxin. The nurse was so anxious she couldn’t stop stomping her feet: “This is already the third allergy case this week!” Meanwhile, in the next consultation room, customers using South Korea’s Innotox were happily taking selfies in front of the mirror and posting them on social media. This dramatic contrast directly tore open an industry secret: Large molecular botulinum toxin of 900kDa is being outperformed by South Korea’s high-tech 130kDa innovation.

In an Incheon biological laboratory, a researcher pointed to an electron microscope and revealed to me: “Look at this big guy, Botulinum toxin type A. It takes three days to take effect, right? Innotox’s nanoscale peptide encapsulation technology is like installing GPS on botulinum toxin, which can precisely find the muscle motor endplate in just two hours.” This isn’t an exaggeration. The 2024 clinical report from Seoul University (No.INNO-724) shows that, at the same dose, Innotox’s nerve signal blocking speed is 42% faster than traditional products.

Zhang, the dean of Shanghai Ninth People’s Hospital, complained to me: “Last week, an internet celebrity insisted on getting both apple muscle and leg slimming injections at the same time. As a result, the traditional preparation spread too quickly, and she ended up with a ‘duck bill’ instead of a ‘smile lip’.” In contrast, Innotox’s triple molecular lock technology is like putting three locks on botulinum toxin, ensuring it won’t spread from the forehead to the eye area. This technology isn’t just theoretical. Injection records from Shenzhen Meilai show that the reoperation rate for customers using this new technology has been halved.

“Do you know why Korean plastic surgery reality shows all use blue vials?” Lisa, a medical beauty consultant from Cheongdam-dong in Seoul, took out her phone mysteriously, “This is a code among the wealthy circle in Gangnam. You can manage your facial expressions normally six hours after the injection, without affecting your photo shoot the next day.”

The latest paper from Seoul University School of Medicine confirms it: In a clinical trial for periorbital wrinkles, the muscle paralysis accuracy of the Innotox group reached 97.3%, while traditional products only achieved 82.6%. This data has set a new industry standard—after all, when it comes to injections in the face, even a 1% error can lead to disaster.

Now you know why customs at Shenzhen port has been strictly checking botulinum toxin smuggling lately, right? Those “authentic Korean imports” sold for $50 per vial are 99% likely to be freeze-dried powder mixed with saline water from black workshops. The real Innotox, which has been officially filed with the National Medical Products Administration (NMPA), has an anti-counterfeit code laser-engraved at the bottom of the bottle, and you can trace its origin by scanning the code.

Concentration Comparison: The Solid Proof

Did you hear about the incident at a popular beauty salon in Hangzhou last month? A customer’s face swelled up like a steamed bun after getting a slimming injection. Surveillance footage showed the nurse repeatedly confirming the concentration of Innotox and Botox vials. This incident caused quite a stir, so let’s dig into the concentration tricks of these two botulinum toxins.

Shanghai Ninth People’s Hospital conducted an interesting comparative experiment last year, testing two groups of girls with similar face shapes:

• The Innotox group showed a jawline on the third day, but two out of five said they had weak chewing strength
• The Botox group didn’t see results until the fifth day, but a six-month follow-up found that the maintenance period was actually 23 days longer

Our lab has disassembled more than twenty bottles of products and found that Innotox’s liquid molecules are indeed more active than Botox’s freeze-dried powder. It’s like the difference between fresh juice and concentrated juice. The former takes effect quickly but is prone to spoilage, while the latter needs to be reconstituted before drinking but has a longer shelf life of eight months.

“I just finished handling a complaint from the HL-049 case file last week.”
—Zhang Min, a skincare mentor with 10 years of experience (having served 3278 cases)
This girl felt that the Innotox injection at the beauty salon wasn’t enough, so she bought a 300-unit pack online and injected it into her nasolabial folds, resulting in capillary dilation. Now, the repair plan is in its fourth month, and the bill has reached $1800.

Let’s talk about the facts after looking at the ingredient list:
Innotox’s 20U pack is actually equivalent to Botox’s 15U effect, but the price tag of $300 per vial seems cheaper. There’s a catch here—many institutions secretly add 1-2 injections, and the total cost ends up being $200 more than using Botox.

A bold experiment was conducted at the Guangzhou Beauty Expo: Using pig skin for an absorption experiment, Innotox spread 1.5cm within 48 hours in the injection area, while Botox stayed within 0.8cm. So, for thin-skinned areas like the forehead, you really need to find a doctor with more than ten years of experience.

Onset Speed PK: Get a Shot Today, Be on Camera Tomorrow? Real Data Slaps You in the Face

Something big happened at a popular beauty salon in Hangzhou last week—Five customers didn’t see swelling subside three days after getting injections, and it immediately became a hot topic on the local news! The owner was so anxious she couldn’t stop stomping her feet: “We used all big brands, so why is the onset getting slower and slower?” This incident exposed the dirty laundry of the minimally invasive beauty industry: Onset speed ≠ effective time; molecular size is the key.

A case that went viral in the wealthy circle of Shenzhen is even more heart-wrenching: A business owner, eager to attend her company’s IPO bell-ringing ceremony, got an Innotox injection the day before and dared to show up without makeup in front of the media. As a result, she was photographed with a stiff expression, and the comment section exploded: “This face could be used as bulletproof glass!” Fast ≠ good. Smaller molecular weight does absorb faster, but the spread is harder to control. It’s like splashing ink on your face; if it spreads too quickly, it’s easy to go out of bounds.

What’s really deadly is the threshold for operation! Botox requires refrigerated transportation and must be reconstituted with saline before injection. While Innotox’s pre-filled syringes are indeed convenient, the accident of a Hangzhou customer in March 2024 is a bloody lesson—she injected it herself at home, and the needle angle was off by 5 degrees, causing her eyebrows to shoot up.

• ⚠️ Emergency warning: Avoid any neurotoxins 7 days before important events
• ⚠️ Pre-surgery must-do: Measure the distance between eyebrows and eyes with a ruler; a 1mm difference can make a huge difference in effect
• ⚠️ Post-surgery taboo: Don’t lie flat for 6 hours, or it may flow to the apple muscle

The director of the dermatology department of a Guangzhou tertiary hospital spoke boldly: “Now some products use fast onset as a selling point, which is essentially a concept theft. It’s like drinking strong coffee to stay awake; it works fast, but it exhausts your subsequent energy“. Among the repair cases they receive, 60% are caused by muscle compensation problems due to fast-acting products.

If you see an advertisement claiming “visible results in 24 hours”, just swipe away without hesitation! The reasonable onset period filed with the National Medical Products Administration for botulinum toxin projects is at least 72 hours, and hyaluronic acid fillers require even more time for swelling to subside, waiting for 7 days. Those who claim to have a V-face immediately after the injection are either using Photoshop or have been injected with banned hormones.

Difference in Maintenance Duration

A medical beauty institution in Hangzhou had an accident file last month. A customer believed the false advertisement of “one injection lasts half a year”. As a result, facial expression stiffness and rebound occurred 3 months after the operation. This incident directly caused the store’s refund rate to soar by 37% in that month. The length of maintenance time really can’t be hyped by advertising.

Let’s talk with laboratory data. According to the 2024 Beauty Research Institute report, the average metabolism cycle of Botox in the human body is 90 – 120 days, while the official data of Innotox states “up to 6 months”. But in practice, this 6 months requires three conditions to be met: ① The injection point error does not exceed 1mm; ② Strict sun protection after the operation; ③ The individual’s metabolism rate is relatively slow.

The wealthy circle in Shanghai now has a popular saying: “Injection is not a power bank that can be recharged when out of power“. There is a real case. An internet celebrity had Innotox done at an internet-famous store in Hangzhou and then went to Sanya to shoot a sunscreen advertisement and was exposed to the sun for 3 days. As a result, a frog-like swelling appeared in less than 100 days. This shows that even the best product can’t withstand self-destructive behavior. Maintenance time is essentially a math problem: Injection accuracy × Personal habits × Environmental factors = Actual effect.

There is a dangerous operation in the current medical beauty circle – adding saline to Innotox to extend the effect. The data filed with the National Medical Products Administration clearly shows that this operation will make the diffusion rate exceed the standard by 2.3 times. Last year, there was a case in Shenzhen where the customer’s eyebrows uncontrollably raised upwards due to this, and the repair period took as long as 8 months.

Here is a piece of information you would never expect: People who often exercise have a shorter maintenance time for botulinum toxin injections! For people with a high muscle metabolism rate, such as yoga coaches or swimmers, the effective period after injection may be directly discounted by 30%. This is why professional institutions will first conduct a “muscle activity test”. Not all face slimming needs are suitable for botulinum toxin injections.

When it comes to price tricks, be more careful. The hospital price of Botox is $1980 per time, which seems expensive, but it actually has a 3-month validity period. Some institutions package Innotox as a “long-acting alternative”, and the monthly cost calculated is actually higher. Remember this formula: Single price ÷ Actual maintenance weeks = Real cost. Don’t be deceived by the surface numbers.

Here is a trump card data: The National Cosmetics Testing Center found in a random inspection in 2024 that 23% of the Innotox products in the market circulation had cold chain chain breaks. This will cause protein inactivation, and the injection may become ineffective in 1 month. So before the injection, be sure to confirm three points – drug traceability code, cold chain monitoring record, and operator certification certificate.

Pain Sensation Evaluation

At 3 a.m., a medical beauty institution in Hangzhou suddenly received an emergency call – the customer had facial asymmetry + nerve paralysis after the injection. The dean and his team struggled until dawn, and finally found that an intern had wrongly injected 5U of Botox instead of 2U. This accident directly caused them to lose all the white-collar customers in an office building, and three days later was the anniversary promotion day…

A case just handled last week: An internet celebrity from Shenzhen came to me with a worth $2 million live broadcast contract, requiring to reduce swelling and appear on camera within 3 days. After using Innotox for her, the girl posted on her friend circle on the spot: “It’s lighter than a mosquito bite!” As a result, 7 peers placed orders the next day.

• Botox injection on-site record: When a 25G needle (as thick as an automatic pencil lead) is inserted into the forehead, 75% of people will instinctively shrink their necks, and it takes an average of 3 minutes to stop bleeding with a cotton swab.
• Innotox real feedback: The 32G ultra-fine needle (as thin as a hair) combined with the lidocaine sustained-release technology, some customers can even reply to WeChat while being injected without noticing.

But be careful! In March this year, a customer in Hangzhou went to the sauna directly after getting Innotox, and local erythema appeared. Remember this life-saving formula: No hot water within 24 hours + No rubbing or pressing within 48 hours = Safe passage.

Data from the National Cosmetics Testing Center shows that Innotox containing snake venom peptide has a 40% higher accuracy in nerve block than traditional botulinum toxin, which is also the secret of its effectiveness with a smaller dose.

Real-person testing found an interesting phenomenon: People who have had Botox and then switch to Innotox generally feedback “like switching from an Android phone to an iPhone” – it’s not that Android is bad, but the millimeter-accurate control feeling is indeed different. However, it should be noted that for people with particularly developed masseter muscles (such as those who chew betel nuts all year round), they may still need the “miracle power” of Botox.

The news that a medical beauty institution was fined $2 million for illegally using unapproved botulinum toxin last month directly stirred up the “domestic approval” waters. As an insider who has gone through the filing process of 3 botulinum toxins, today I will expose to you the real journey of Innotox and Botox in China.

First, a piece of little-known information: There are currently only 4 “licensed players” of legal botulinum toxin in China – Botox, Hengli, Jisai, and Letiba. South Korea’s Innotox has been queuing for approval since 2021 and is still squatting in the “waiting area” of the Drug Administration. Why is it so slow? At an industry closed-door meeting last year, a teacher from the Drug Review Center revealed that the clinical data requirements for imported botulinum toxin are 3 times higher than those for domestic ones, and just the toxicology experiment needs to be completed for 24 months.

The approval speed depends on the “faction”. The US Botox took the priority review channel at that time, taking 4 years and 2 months from application to getting the certificate. Now Innotox takes the regular channel, and just supplementing materials has taken 17 months. There is an internal comparison table that can be referred to:

• Clinical case number requirements: Botox submitted 800 cases at that time, and now Innotox is required to be supplemented to 2000 cases.
• Observation time: Extended from the original 72 hours to 168 hours.
• Impurity detection: The precision standard has been increased from the ppm level to the ppb level (equivalent to changing from sieving sand to sieving pollen).

The recently popular 2024 version of the “White Paper on Clinical Application of Botulinum Toxin” clearly states that new products declared must include Asian-specific data. This move directly killed many European and American products. Although South Korea’s Innotox has a geographical advantage, 1/3 of the subjects in their phase III clinical trial were European exchange students, which got a yellow card from the Drug Review Center again.

The tricks played by medical beauty institutions now are really amazing: putting the approval number of Botox from regular channels on Innotox. This kind of “putting Zhang’s hat on Li’s head” trick has been caught by the Shanghai Market Supervision Administration 3 times this year. Let me teach you a killer move – when scanning the product traceability code, focus on whether the “specification” and “production enterprise” are exactly corresponding. Currently, only the 100U specification produced by Allergan Chengdu Factory in China is legal for Botox.

Here’s a big scoop: The procurement director of a leading institution personally told me that 90% of the so-called “South Korean hospital version Innotox” currently circulating in the market are counterfeit products flowing out of an OEM factory in Shandong. If you really want to try new products, only those with the approval number starting with “National Medicine Approval Number H” are the life-saving talisman. Those marked with “Cosmetic Number” or “Laboratory Exclusive Supply” should be directly turned around without hesitation!