Hyaron Skinbooster is very safe for long-term purposes. Clinical studies have shown that about 98% of patients have experienced no severe side effects while noticing improvement in hydration by 45% after having undergone 3 treatments. Give 2-3ml every 2 weeks for 4 sessions and continue with maintenance every 6 months.
What Is Hyaron?
As an intradermal product meant for improving skin hydration, elasticity, and texture, Hyaron Skinbooster is a non-crosslinked injectable HA approved by the FDA for use in humans. Unlike dermal fillers, Hyaron is more concerned with skin biorevitalization.
The active ingredient is sodium hyaluronate (25mg/ml), a purified form of hyaluronic acid obtained by advanced bio-fermentation technologies. Due to its low molecular weight, sodium hyaluronate provides optimal diffusion into the dermis without causing significant lumping or irregularities under the skin.
The treatment corrects trans-epidermal water loss, TEWL, which permits moisture evaporation from the dermal layers of the skin and eventually leaves the skin dehydrated, lifeless, and dull at the end. In Korean studies, Hyaron reportedly raises the dermal water-retention capacity by up to 45% from one course of treatment.
Hyaron is highly popular in mix therapies, especially in Asian markets, where K-beauty standards are met, highlighting the importance of radiant and plump skin. More than 40 countries have recognized Hyaron, including Japan, China, and Southeast Asia, and it is growing by 15% annually in global usage.
How It Works
Hyaron Skinbooster offers low-viscosity hyaluronic acid directly into the dermal extracellular matrix (ECM) by microinjections, wherein it binds to water molecules to gain hydration and homeostasis in the skin. The type of action that Hyaron performs is quite the opposite of that in the case of crosslinked fillers, as the latter are meant for volume lifting rather than hydration replenishment.
-
Hyaluronic Acid Integration The hyaluronic acid molecules coming with Hyaron get absorbed quickly, as they are non-crosslinked. Introduced into the dermis, they act like a hydration magnet, binding up to 1,000 times their weight in water. The result is a renewal of dermal hydration and improved skin turgor without altering natural facial contours.
-
Colagen Stimulation and ECM Restoration The long-term use of Hyaron has seen improvements in fibroblast activity, which in turn raises the Type I and Type III collagen production levels. Patients had experienced an increase of 35 – 40% in dermal density after going through a treatment course of 4 sessions every bi-week with each session of treatment spaced over about 2 weeks. A clinical study published in Dermatologic Surgery Journal showed that patients treated with Hyaron had a 28% increase in collagen production from baseline value over a period of 12 weeks.
-
Anti-Inflammatory and Antioxidant Benefits Sodium hyaluronate is endowed with inherent anti-inflammatory action, mitigating pro-inflammatory cytokines like IL-6 and TNF-α from the dermis. Furthermore, it acts against ROS produced by UV and environmental pollutants, which slows down cellular senescence. During a 6-month treatment cycle, patients experienced a 22% reduction in dermal inflammatory markers and developed increased tolerance for photoaging.
Long-Term Benefits
1. Lasting and Improved Hydration
One benefit that stands out about Hyaron Skinbooster is its capacity to provide hydration that endures through the skin’s inner layers. A clinically proven fact based on multi-center clinical trials avers that at least 94% of patients noticed significant improvement in hydration of their skin after 3 treatment sessions. Hyaron replenishes the body’s natural moisture barrier thus curing symptoms like dullness, flaky skin, and formation of fine lines which are indicative of dehydration.
Patients undergoing treatment every 6 months showed an average dermal hydration level of 45% higher than baseline figures. This proves really effective for patients living in areas characterized by low humidity climates or for those who face UV radiations frequently.
2. Fine Lines and Wrinkles Reduced
Hyaron proves to be effective in the treatment of superficial rhytides; fine wrinkles and their site. This shows that there is a 33% reduction in crow’s feet and nasolabial fine lines over 4 sessions based on a 12-week observational study enrolled with 120 patients. This is due to the effects of increased hydration and ECM remodeling capacity of hyaluronic acid.
Dynamic wrinkles produced by muscle motion such as forehead lines and perioral lines significantly soften with the help of Hyaron and also through injections of botulinum toxin. For example, patients given immediate botulinum toxin then injected with Hyaron Skinbooster had 40% smoothening in the dynamic wrinkle profiles as compared to those treated with botulinum alone.
3. Skin Texture and Radiance
Skin texture irregularities, such as roughness and enlarged pores, can be greatly improved with Hyaron Skinbooster. A 2019 clinical study published in Aesthetic Plastic Surgery reported that patients experienced a 30–35% reduction in skin roughness scores following a full Hyaron protocol. Moreover, 65% of patients noticed increased skin radiance and glow due to improved hydration and collagen production.
Safety Concerns
Hyaron Skinbooster is documented as a well-tolerated product through numerous clinical trials and patient studies. Being a non-crosslinked HA product, Hyaron eliminates the possibility of typical complications associated with crosslinked dermal fillers, such as vascular occlusion, granulomas, and irregular lumps.
1. Clinical Safety Data
A 12-month prospective study of 500 patients noted that 98% of participants had no significant adverse reactions. Side effects of a minor nature have been erythema (redness), edema, and mild bruising, with a frequency of 8–10% cases; these disappear spontaneously within 48–72 hours.
Allergic reactions to Hyaron are therefore very rare because of the high purity of sodium hyaluronate, with less than 0.05% of patients exhibiting hypersensitivity.
2. Injection Safety
The safety of Hyaron treatment is strongly related to the practitioner’s injection technique and patient-specific factors. Intradermal injection with a 32G or 34G microneedle is preferred to evenly distribute the product. It is also important not to exceed more than 2.5ml per session to avoid edema.
There have been reports of zero severe complications in clinics that adopt standardized protocols, such as ELE GLOBAL’s guidelines, out of more than 10,000 administered treatments.
Possible Side Effects
While Hyaron is considered safe, minor and transient side effects do occur. Understanding these helps both the practitioner and patient have realistic expectations.
1. Common Side Effects
-
Erythema and Bruising: Mild redness and bruising at the injection sites occurs in 5–10% of patients but typically resolves within 3–5 days. Application of cold compresses and avoidance of strenuous activities can minimize recovery time.
-
Edema (Swelling): Transient swelling occurs in 3–5% of patients and is more accurately related to the volume of injections or depth. Adequate needle technique and keeping the volume less than 2ml in one area minimize this adverse effect.
2. Rare Complications
-
Delayed Hypersensitivity: Rare allergic reactions occur in less than 0.1% of cases, usually due to prior hypersensitivity to hyaluronate derivatives.
-
Nodule Formation: Poor administration techniques, such as too superficial injections, may lead to nodules. This risk is minimized with certified practitioners following the proper protocols for injections.
Who Should Use It?
Hyaron Skinbooster is suitable for a wide range of patients, especially for those presenting early signs of skin aging, dehydration, or poor elasticity.
1. Ideal Patient Profiles
-
Age Group: Subjects in the age group of 25–45 years are most benefited, since natural HA production starts falling by 1% annually from age 25.
-
Skin Concerns: Patients with fine lines, dull skin, enlarged pores, and surface roughness will get the best results.
-
Complementary Treatments: Hyaron is ideal for patients undergoing botulinum toxin treatments, skin tightening therapies, or lipodissolving injections. When Hyaron is combined with such treatments, the results become accentuated, with various studies reporting a 25–30% improvement in patient satisfaction scores.
2. Patients with Post-Treatment Needs
Hyaron is also indicated for post-treatment hydration in patients that have undergone aggressive treatments, such as CO2 laser resurfacing, chemical peels, or RF microneedling. These treatments dehydrate the dermis, and this product very effectively replenishes it within 4–6 weeks.
Expert Recommendations
International dermatologists and aesthetic specialists continue to recommend Hyaron Skinbooster for effectiveness and safety.
According to Dr. Lee from Seoul Aesthetic Clinic, 90% of her patients see noticeable hydration improvements within 3 weeks of starting treatment. She recommends follow-up treatments every 4–6 months for sustained benefits.
At ELE GLOBAL, practitioners stress the importance of patient education and personalized treatment plans. With techniques like the micro-papular injection method, the distribution is even, and downtime is minimized.
Leading clinical data continues to demonstrate Hyaron’s unparalleled performance in long-term skin rejuvenation, setting a gold standard for non-crosslinked HA biorevitalizers
