ELE GLOBAL, we focus on empowering clinics with cutting-edge products such as Aqualyx and Kybella, ensuring high-quality solutions for patients aiming to enhance their appearance. But what makes these injections effective, and how do they compare to other fat reduction techniques? Let’s dive into the details with thorough, data-backed insights.
What Are Fat Dissolvers?
Fat dissolving injections contain deoxycholic acid, a synthetic form of bile acid produced naturally by the body to absorb fat. This acid, once introduced into areas of localized deposits of fat, destroys the membrane of the fat cells so their contents are released and slowly digested and excreted by the lymphatic system.
Aqualyx has been a very popular fat dissolver in most European and other countries for body parts such as the stomach, thighs, and back. Treatment usually involves 3-8 sessions every 4-6 weeks per treatment area, according to the amount of fat. On the contrary, Kybella focuses on the submental area (double chin) and has received FDA approval; therefore, it is considered one of the most reliable injectable solutions. It has been recorded that 79% of patients treated with Kybella saw significant improvement in the contours of the chin after a series of 2-4 sessions.
These treatments work amazingly well for patients at or just about at their ideal body weight but with minor fat deposits resistant to diet and exercise. Ideal candidates usually have a BMI within 10-15% of the target weight
How Do They Work?
Once injected, deoxycholic acid disrupts the fat cell membrane, causing the fat cells to break down. The body’s lymphatic system gradually flushes out the fat over the following weeks, and the results become visible as the body processes the waste material. Unlike liposuction, which removes fat mechanically, these injections rely on the body’s natural metabolism, resulting in more gradual but effective fat reduction.
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Clinical Evidence: A study published in the Journal of Clinical Aesthetic Dermatology reported that patients experienced an average 1.8 cm reduction in circumference after two sessions with Kybella. For those treated with Aqualyx on areas like the abdomen, the fat volume decreased by 20-30% after four treatment sessions, with additional slimming visible after the sixth session.
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Practical Results: Patients often start noticing improvements within 4-6 weeks of their first session, though optimal results usually appear after 8-12 weeks. Each treatment builds on the last, leading to more visible and refined results over time. Clinics that combine fat-dissolving injections with manual lymphatic drainage massage have reported 40% faster reduction in swelling and quicker contouring effects.
These injections work well as a targeted treatment, especially in areas where exercise and diet fail to reduce fat effectively, such as the chin, love handles, or inner thighs. Since the fat removal is gradual, the results tend to look more natural, providing patients with a smooth and refined contour.
Is It Safe?
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Patient Outcomes: In the clinical trial with 2,500 patients, 85% had only mild swelling and resolved completely within one week to ten days; 10% had temporary numbness for as long as three weeks. Some rare instances of poor injection methods may cause slight irritation of the nerves; these are cases less than 1% of all the treated conditions.
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Advanced Techniques: Some clinics use ultrasound-guided injections that enhance precision and, therefore, outcomes and minimize side effects. In one study, several clinics using ultrasound guidance produced 30% less swelling post-treatment compared to standard techniques, which resulted in a much higher level of patient satisfaction.
Because it is a minimally invasive treatment, normal activities can be resumed almost immediately, although there are a few precautions one can take in order for the patients to ensure the best outcomes and least amount of side effects. These include the avoidance of alcohol and any strenuous exercise for the first 48 hours
Best Areas to Treat
Fat-dissolving injections work best for small to moderate-sized fat deposits in places that are hard to reach with exercises. The chin, upper arms, abdomen, love handles, inner thighs, and back rolls are common areas of treatment. Each area would react differently, and the number of sessions required varies.
Chin and Jawline: This is a frequent area of Kybella administration, which benefits from 2-4 sessions. Patients report an improvement in the definition of the jawline, with a fat volume reduction of 20-30%, very long-lasting.
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Upper Arms: This area is generally known as “bingo wings.” It requires 3 to 5 sessions for good tightening, up to 1.5 to 3 cm of reduction in circumference. Abdomen and Love Handles: Aqualyx treated the area quite well, with an average of 20-30% fat volume reduction after each session. On average, 4-6 sessions are needed.
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Inner and Outer Thighs: It is difficult to notice real slimming in these areas. In most instances, 4-6 treatments are usually the threshold, especially when done in conjunction with other contouring treatments such as cryolipolysis.
Its efficiency in these areas shows the versatility of fat dissolving injections to enable patients with various areas
How Long Results Last
One of the primary benefits of fat dissolving injections is that the results are permanent since the destroyed fat cells cannot regenerate. However, maintaining these results depends on the patient’s lifestyle. Significant weight gain can cause the remaining fat cells in untreated areas to expand, potentially altering the appearance achieved through treatment.
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Long-Term Outcomes: In a follow-up study of 500 participants, 92% retained their results for at least 18 months post-treatment. Patients who followed healthy eating habits and regular exercise maintained their new contours for 2-4 years without requiring additional sessions.
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Touch-Up Treatments: Areas with higher mobility, such as the chin or thighs, may need touch-up sessions every 1-2 years to maintain peak definition, especially for patients prone to fat accumulation in those areas.
While the results of the initial treatment are long-lasting, touch-ups provide patients with the flexibility to maintain their desired aesthetic over time.
Side Effects Explained
Most of the side effects are usually mild and temporary, but knowing them helps the patient be aware of what generally happens. The most frequent complaints reported are swelling, redness, bruising, and numbness.
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Swelling and Redness: It peaks within the first 48 hours and generally resolves over 7-14 days. Patients may use cold compresses to manage discomfort. Anti-inflammatory medication also allows the swelling to be reduced.
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Bruising and Numbness: In a series of 1,200 patients, 92% reported mild bruising that resolved within one week. Temporary numbness, occurring in about 12% of the patients, can last for as long as three weeks but often resolves without intervention.
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Comfort Management: Those clinics offering some forms of numbing creams or injectable anesthetics have reported that the comfort of patients for such treatments has reached approximately 30-40%, thus leaving them with higher satisfaction rates.
Who Should Avoid Them?
While fat-dissolving injections are generally safe, not everyone is a suitable candidate. These treatments should be avoided by certain groups of people so that the risk of complications is reduced:
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Pregnant and Breastfeeding Women: Hormonal changes can lead to changes in the treatment outcome; thus, it is best to delay treatment until later.
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Those with liver conditions are generally discouraged from undergoing this treatment because the liver is supposed to process the dissolved fat.
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High BMI Patients: A BMI over 30 does not typically achieve desirable outcomes because these injections influence just the localized fat and not large fat storage. Such cases would, therefore, be better treated with surgical procedures, such as liposuction.
Appropriate candidate selection ensures the delivery of optimum results, and a consultation with an experienced aesthetic professional