Results start to become visible within 24-48 hours; 85% of people are satisfied after a single session. Generally, 0.2-0.5 mL of dissolver is used per 1 mL of filler to accomplish ideal refinement.
What Are Filler Dissolvers
Dermal filler dissolvers are solutions based on the main ingredient of hyaluronidase, which is an enzyme catalyzing the breakdown of hyaluronic acid-based fillers. Hyaluronic acid fillers (HA), such as Juvederm, Restylane, and Belotero, are in high demand due to restoring volume, contouring the face, and filling wrinkles; however, results could sometimes turn out to be unsatisfactory or complications may occur. Dissolvers create a good alternative for modifying or completely reversing the effects of fillers.
It has also been noted by aesthetic clinics that 5-10% of patients request partial or total reversal of dermal fillers within one month of treatment. The dissolving process generally begins within a frame period of 24 hours, with the majority of the fillers totally dissolved in two to three days. On using larger areas such as the jawline, practitioners may indicate that sessions of dissolver should be a week apart for best results within 7-14 days to avoid swelling or discomfort.
Following 2023 aesthetic trends, the demand for dissolvers went up by 35% worldwide, while the significant growth was marked across countries including South Korea, the UK, and the United States. Similarly, clinics are reporting an increase in patients who require refinements to overfilled lips or asymmetrical cheek enhancements, thereby making dissolvers essential for clinics specializing in facial aesthetics.
How Do Dissolvers Work
The addition of hyaluronidase causes the breakdown of hyaluronic acid molecules into smaller fragments through hydrolysis, which the body can degrade naturally. Depending on the amount and depth of the filler, one may begin to see results in just one day, but complete dissolution may require multiple sessions.
For instance, migrated or puffy under-eye fillers would take 2 to 3 injections spaced a few days apart, which ensures the area goes back to looking natural and not saggy. On the other hand, lip fillers will dissolve a bit faster because less volume is used; usually, visible improvements could be observed right after the first treatment.
Clinics recommend 0.2 to 0.5 mL of hyaluronidase per 1 mL of filler for minor adjustments; however, larger volumes may be required in enhancements of, for instance, the jawline, which can require as much as 1 mL of dissolver per session. This makes for precise contour fine-tuning to avoid over-dissolving and an imbalanced outlook of the face.
When Should You Use Them
Dissolvers typically come into play with instances of filler complications, dissatisfaction with the aesthetic of the result, or when a customer wants to make a change. In 20% of filler procedures, irregularities will be noticed by patients in the form of unevenness, excess volume, or inadvertent product migration. This is most frequently seen around the areas of the lips and under-eyes, where the filler will often shift over time.
More serious instances of vascular occlusion—a blockage of the blood vessels due to the filler—can have tissue saved from necrosis with the immediate use of dissolvers. Protocols for emergency dissolving propose the administration of 150-300 units of hyaluronidase per area affected, ensuring the restoration of blood flow in 2 to 4 hours and hence minimal permanent damage.
Some patients also seek dissolvers for aesthetic refinement. For instance, patients who had aggressive cheek enhancements may want to be made to look more natural, and the dissolvers offer the practitioner an opportunity to refine such results without the need for new filler treatments.
Are Dissolvers Safe
Dissolvers are generally safe, provided the procedure is performed by professionals. As with any form of injection, there is an element of risk involved in the treatment. Possible minor side effects include mild redness, swelling, or bruising; these usually settle within 48-72 hours.
While allergic reactions to hyaluronidase are rare, they do occur, and most specifically in individuals allergic to bee venom. A 2021 clinical review showed this product caused mild allergic reactions, treated with antihistamines, in only 5 out of 1,000 patients. A lot of clinics recommend a patch test to hedge against such risk, which is the policy for those clinics that ELE GLOBAL supplies.
The studies show that more than 90% of the patients obtained a satisfactory result after the first session of dissolver, while 10-15% can require further treatments with the purpose of refining the result. This demonstrates the importance of cautious management of the dose to balanced results.
Dissolvers vs. Botox
Although both dissolvers of fillers and Botox are important tools in aesthetic medicine, they differ in their intended use. Whereas Botox, or the botulinum toxin, is used mainly for facial muscle relaxation and ironing out dynamic wrinkles, dissolvers take care of filler-related irregularities or overcorrections.
For instance, Botox can serve ideally on the forehead, crow’s feet, and glabellar lines, which develop through the motion of muscles. Dissolvers are, in turn, suitable for places that need refining due to over-application or migration of the fillers, like the lips or nasolabial folds. Some clinics will also offer combined treatments: Botox and fillers, each with dissolvers, are strategically applied to achieve a natural long-lasting outcome.
It could even be in one session that a patient who receives both treatments may get Botox to relax lines on the forehead while using a dissolver to correct the excess in the cheek area. This actually allows for more symmetrical facial aesthetics; any imbalance in muscle activity is complemented with just the right distribution of volume.
How Soon Will You See Results
In dissolver injections, the results of noticeable improvement can be witnessed within a period of 24-48 hours, while the complete breakdown may take around 3 to 5 days. In cases of corrections at sensitive areas, improvements can appear rather gradually within 5 to 7 days. This could also reduce the associated risks of puffiness or sagging.
A case study from an aesthetic clinic based in the UK reported that 85% of its patients experienced satisfactory results after their first dissolver session, whereas 15% needed additional sessions for precise touch-ups. Corrections in lip fillers tend to result in 80-90% improvement in one session, which makes them one of the most commonly performed areas where dissolvers are used.
Improvement of Aesthetic Outcomes
Adding the dissolvers into the treatment planning for the dermal fillers helps to facilitate flexibility in the creation of the most desirable outcomes, greatly increasing patient satisfaction. Such clinics offering dissolvers in addition to other aesthetic solutions report an increase in patient retention by 30% due to reassurance the clients have in knowing they have options for adjustment.
Practitioners also recommend adding dissolvers to a comprehensive contouring treatment of the face. For example, small amounts of filler followed by dissolvers have been indicated to fine-tune the final result in those clients receiving fat-dissolving injections or Botox for slimming the jawline. ELE GLOBAL’s dissolver kits, designed from quick corrections to more complex procedures, give practitioners the freedom to seamlessly adjust and change treatments as the client’s needs evolve.
For facial aesthetics, dissolvers have become indispensable with their ability to quickly and safely readjust aesthetic outcomes. They give both the patient and practitioner confidence in any treatment to make the most satisfying natural result, be it for minor tweaks or for emergency interventions