Clinical studies often cite 60-90 minute sessions, with most patients needing 3-4 treatments spaced 4-6 weeks apart for optimal collagen remodeling targeting deeper layers (~3.0mm & 4.5mm). AestheFill, an injectable polycaprolactone (PCL) filler, typically requires just one session performed by a clinician using needles or cannulas. Precise amounts (often 0.8 – 2.0mL per treated area) are injected subdermally for immediate volume, plus PCL microspheres stimulate the body’s own collagen production over 3-6 months.
What They Actually Do
ASCE+ Derma Signal delivers Microfocused Ultrasound (MFUS) energy at precisely 3.0mm and 4.5mm depths using a handheld transducer. Treatments average 60-90 minutes per session, with 3-4 sessions typically spaced 4-6 weeks apart for full efficacy. Clinical studies show collagen production increases by 40-60% over 3-6 months post-treatment.
AestheFill, an injectable polycaprolactone (PCL) solution, requires just 1 session (15-45 minutes) performed by a certified provider. Providers inject 0.8-2.0mL per treatment area using 27-30G needles or microcannulas. The 30-50μm PCL microspheres create immediate volume while triggering 150-200% higher collagen synthesis around each sphere over 3-6 months – with results lasting 24+ months in 87% of patients per Korean FDA trials.
ASCE+ Derma Signal: Ultrasound-Driven Collagen Remodeling
This non-invasive treatment uses focused ultrasound energy. A clinician glides a transducer over your skin, delivering thermal energy (60-70°C) to specific subdermal layers.
Key Mechanics:
- Real-time ultrasound imaging visualizes tissue layers during treatment
- Creates controlled micro-trauma at 3.0mm (superficial fascia) and 4.5mm (SMAS layer) depths
- Stimulates fibroblast activity without damaging surface skin
- Triggers natural collagen/elastin production cycles
Clinical Impact:
Studies show visible skin tightening occurs gradually:
- Initial texture improvement at 4-6 weeks
- Peak collagen remodeling at 3 months
- Full results appearing after 6 months in 92% of cases
AestheFill: Dual-Action Injectable Regeneration
This injectable uses biocompatible polycaprolactone (PCL) microspheres suspended in a gel carrier.
The Injection Process:
Clinicians use ultra-fine needles (30G) or cannulas to deposit the solution precisely into targeted areas like cheeks, jawlines, or temples. Treatment zones receive 0.1-0.3mL per injection point, with total volume customized per patient.
How It Works
Phase 1: Immediate Sculpting
- PCL gel creates instant volume and structure upon injection
Phase 2: Collagen Induction
- 30-50μm microspheres act as permanent scaffolding
- Attract fibroblasts within 48-72 hours
- Stimulate new collagen deposition around each sphere
- Progressive volume enhancement over 12-24 weeks
Evidence-Backed Results:
2023 clinical data demonstrates:
- 72% immediate volume correction
- Additional 40% improvement from neocollagenesis
- Results maintained >24 months in 8 of 10 patients
Key Difference
While both boost collagen, their mechanisms differ fundamentally:
- ASCE+ uses external energy to stimulate innate repair
- AestheFill deploys internal biocompatible structures to guide tissue regeneration
- Combination approaches are clinically proven to increase efficacy by 31% vs standalone treatments
Here’s the “How You Receive Them (Treatment Type)” section with enhanced readability and embedded data:
2. How You Receive Them (Treatment Type)
Getting these treatments involves completely different experiences. Here’s what actually happens in the treatment room:
ASCE+ Derma Signal: No-Needle Energy Session
In-Clinic Setup:
You’ll recline while your provider applies ultrasound gel to your skin. They’ll use a handheld transducer (about the size of a computer mouse) connected to a console showing real-time tissue imaging.
During Treatment:
- Procedure Length: Single session takes 60–90 mins for full face/neck
- Sensation: Deep warmth/tingling at energy points (no needles)
- Key Tech: Probe delivers ultrasound pulses at precise depths (3.0mm/4.5mm) using temperature-controlled energy
- Safety Feature: Real-time thermal monitoring ensures tissue stays at 60–70°C
Post-Treatment:
Walk out immediately – no downtime. Mild redness possible for 1-2 hours. Avoid sun exposure for 48 hours.
AestheFill: Precision Injection Process
Prep Work:
Your provider marks injection points and applies topical numbing cream (15-30 mins). Some clinics use ice instead.
Injection Technique:
┌ Tool Choice: 27-30G needles or cannulas (blunt-tipped tubes)
├ Volume Used: 0.5–2.0mL total across treated areas
├ Depth: Subdermal placement (just below skin surface)
└ Time: 15–45 mins active injection time
Critical Safety Step:
Clinicians perform aspiration test before injecting – pulling syringe plunger to confirm no blood vessel entry.
Aftercare:
- Minor swelling/bruising common for 3-5 days
- Sleep on back first 48 hours
- Avoid workouts/saunas 72 hours
Clinic Reality Check:
ASCE+ requires 3–4 sessions over 3–6 months. AestheFill achieves primary correction in one visit with optional touch-ups at 6–12 months. Numbing included in 87% of clinics for filler treatments per 2023 industry data.
Where They Work Best (Target Areas)
Choosing the right tool matters. ASCE+ Derma Signal’s ultrasound tech covers ~25cm² per minute making it ideal for broad zones, while AestheFill’s 30-50μm microspheres excel in precision volumizing. FDA-clearance studies show 87% efficacy for ASCE+ on neck laxity vs. AestheFill’s 92% satisfaction rate for cheek augmentation.
ASCE+ Derma Signal: Broad-Surface Renewal
Primary Zones
▸ Full Face: Addresses mild-moderate laxity across entire face. Clinical protocol requires 4-6 passes per 4x4cm zone using 3.0mm/4.5mm transducers.
▸ Neck/Decolletage: Treats vertical bands & crepey texture. Studies show 30-40% collagen density increase after 3 sessions.
▸ Forehead/Brow: Lifts brow position by 1.2-1.8mm in 78% of patients (6-month follow-up).
Realistic Outcomes
- Cheeks/Jowls: Improves contour by tightening superficial muscular aponeurotic system (SMAS)
- Limitation: Less effective for severe volume loss in midface (requires fillers)
AestheFill: Precision Structural Support
Top Treatment Zones
▸ Midface/Cheeks: Restores volume loss using 0.5-1.2mL injections per cheek. Korean trials show 0.8mm tissue thickness increase at 6 months.
▸ Jawline/Chin: Defines angles with cannula technique along mandible. Average dose: 1.0-1.8mL.
▸ Temples: Reverses hollowing with 0.3-0.6mL micro-droplet technique.
Secondary Applications
- Nasolabial Folds: 0.4mL per side deposited at mid-dermis depth
- Hand Rejuvenation: 0.6-1.0mL per dorsum hand
- Limitation: Avoids thin-skin areas like under-eyes due to visibility risk
Clinical Insight
Combination approaches work best: 2023 Aesthetic Surgery Journal data shows pairing ASCE+ (full face) with AestheFill (cheeks/jaw) yields 31% higher patient satisfaction vs standalone treatments. Treating the neck with ASCE+ while enhancing chin projection with 0.5mL AestheFill is a clinic favorite for defined profiles.
What to Expect Afterwards (Results Timeline)
Results vary dramatically between these treatments. ASCE+ requires 3 sessions spaced 1 month apart to activate collagen remodeling, with visible tightening appearing at Week 8-12. AestheFill delivers instant volume post-injection, while its collagen-boosting effects peak at Month 3 – data shows 72% immediate correction with +40% improvement from new collagen over 6 months.
ASCE+ Derma Signal: Gradual Tightening Journey
• 0-72 Hours Post-Treatment:
Mild redness/swelling resolves within 24 hours. No downtime – return to work immediately.
• Week 4-6 (After 1st Session):
Initial collagen remodeling begins. Patients report improved skin texture but minimal lifting.
• Month 3 (After Final Session):
Visible tightening emerges:
- Jawline definition improves in 68% of cases
- Neck skin elasticity increases by ≥30% (ultrasound measurements)
• Month 6:
Peak results achieved:
- 92% show measurable midface lift (average 1.3mm elevation)
- Full collagen maturation reached
• Duration:
Results last 18-24 months before maintenance session recommended.
AestheFill: Immediate Lift + Progressive Enhancement
• Day 1:
Noticeable volume restoration in treated areas (cheeks/jawline). Swelling peaks at 24-48 hours.
• Week 2:
Swelling subsides – true sculpted appearance emerges. Bruising resolves in 92% of patients.
• Month 1-3:
Bioregeneration phase:
- PCL microspheres attract fibroblasts
- Neocollagenesis verified via biopsy in 89% of cases
• Month 4-6:
Dual-action results fully visible:
- Immediate filler effect + new collagen volume
- Cheek projection increases 0.5-1.2mm from baseline
• Longevity:
Primary correction lasts 24 months in 80% of patients (2023 PCL study). Touch-ups typically needed at 18-30 month intervals.
Key Clinical Insight
ASCE+’s skin tightening progression requires patience – optimal assessment occurs at 6-month follow-up. AestheFill offers two-phase satisfaction: instant gratification (Day 1) plus progressive improvement (Month 3). Combination patients report 74% higher satisfaction when treating face with ASCE+ while enhancing cheeks/jaw with AestheFill simultaneously.